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Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vsaspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial

Authors :
Vranckx, Pascal
Valgimigli, Marco
Jüni, Peter
Hamm, Christian
Steg, Philippe Gabriel
Heg, Dik
van Es, Gerrit Anne
McFadden, Eugene P
Onuma, Yoshinobu
van Meijeren, Cokky
Chichareon, Ply
Benit, Edouard
Möllmann, Helge
Janssens, Luc
Ferrario, Maurizio
Moschovitis, Aris
Zurakowski, Aleksander
Dominici, Marcello
Van Geuns, Robert Jan
Huber, Kurt
Slagboom, Ton
Serruys, Patrick W
Windecker, Stephan
Abdellaoui, Mohamed
Adlam, David
Akin, Ibrahim
Albarran Gonzalez-Trevilla, Agustin
Almeida, Manuel
Alves Lemos Neto, Pedro
Aminian, Adel
Anderson, Richard
Andreae, Rick
Angioi, Michael
Asano, Taku
Barbato, Emanuele
Barlis, Peter
Barraud, Pascal
Benit, Edouard
Bertrand, Olivier
Beygui, Farzin
Bolognese, Leonardo
Botelho, Roberto
Bouwman, Coby
Bressers, Marco
Brunel, Philippe
Buszman, Pawel
Buysschaert, Ian
Canas da Silva, Pedro
Carrie, Didier
Cequier, Angel
Chichareon, Ply
Chin Chang, Chun
Chowdhary, Saqib
Collet, Carlos
Colombo, Antonio
Cotton, James
Cruz Ferreira, Rui
Curello, Salvatore
Curzen, Nick
de Bot, Judith
de Vreede, Tone
Delle Karth, Georg
Dijksma, Lynn
Dominici, Marcello
Édes, István
Eeckhout, Eric
Eitel, Ingo
Faluközy, József
Fath-Ordoubadi, Farzin
Ferrario, Maurizio
Fontos, Geza
Francisco Diaz, Jose
Freitas Quintella, Edgard
Frey, Bernhard
Friedrich, Guy
Galasko, Gavin
Galuszka, Grzegorz
Gama Ribeiro, Vasco
Garg, Scot
Gargiulo, Giuseppe
Geisler, Tobias
Gelev, Valeri
Ghandilyan, Art
Goicolea, Javier
Gori, Tommaso
Gragnano, Felice
Guimarães, Ana
Hamm, Christian
Haude, Michael
Heg, Dik
Heijke, Pieter
Hernández Antolin, Rosa Ana
Hildick-Smith, David
Hillen, Dorien
Hoekman, Ina
Hofma, Sjoerd
Holmvang, Lene
Hoole, Stephen
Horváth, Iván
Huber, Kurt
Hugense, Annemarie
Ibrahim, Karim
Iñiguez, Andres
Isaaz, Karl
Jambrik, Zoltán
Janssens, Luc
Jasionowicz, Pawel
Jonk, Judith
Jung, Werner
Jüni, Peter
Katagiri, Yuki
Kogame, Norihiro
Koh, Tian Hai
Koning, René
Konteva, Mariana
Kőszegi, Zsolt
Krackhardt, Florian
Kreuger, Yvonne
Kukreja, Neville
Ladan, Boudijn
Lantelme, Pierre
Leandro, Sergio
Leibundgut, Gregor
Liebetrau, Christoph
Lindeboom, Wietze
Macaya Miguel, Carlos
Mach, François
Magro, Michael
Maillard, Luc
Manavifar, Negar
Mauri, Laura
McFadden, Eugene
Merkely, Bela
Miyazaki, Yosuke
Młodziankowski, Adam
Moccetti, Tiziano
Modolo, Rodrigo
Möllman, Helge
Morelle, Jean-François
Moschovitis, Aris
Munndt Ottesen, Michael
Muurling, Martin
Naber, Christoph Kurt
Neumann, Franz-Josef
Oldroyd, Keith
Ong, Paul
Onuma, Yoshinobu
Palsrok, Sanne
Petrov, Ivo
Plante, Sylvain
Prokopczuk, Janusz
Rademaker-Havinga, Tessa
Raffel, Christopher
Rensing, Benno
Roffi, Marco
Royaards, Kees-Jan
Sabate, Manel
Schächinger, Volker
Seidler, Tim
Serra Peñaranda, Antonio
Serruys, Patrick
Sikarulidze, Lali
Slagboom, Ton
Soliman, Osama I
Sousa, Amanda
Spitzer, Ernest
Stables, Rod
Steg, Gabriel
Steinwender, Clemens
Subkovas, Eduardas
Suryapranata, Harry
Takahashi, Kuniaki
Talwar, Suneel
Teiger, Emmanuel
ter Weele, Addy
Teurlings, Eva
Thury, Attila
Tijssen, Jan
Tonev, Gincho
Trendafilova-Lazarova, Diana
Tumscitz, Carlo
Umans, Victor
Ungi, Imre
Valkov, Veselin
van der Harst, Pim
van Geuns, Robert Jan
van Meijeren, Cokky
Vassilev, Dobrin
Velchev, Vasil
Velthuizen, Esther
Verheugt, Freek
Vlcek, Natalia
vom Dahl, Jürgen
Vrolix, Mathias
Walsh, Simon
Werner, Nikos
Windecker, Stephan
Witsenburg, Maarten
Zaman, Azfar
Żmudka, Krzysztof
Zrenner, Bernhard
Zurakowski, Aleksander
Zweiker, Robert
Source :
The Lancet; September 2018, Vol. 392 Issue: 10151 p940-949, 10p
Publication Year :
2018

Abstract

We hypothesised that ticagrelor, in combination with aspirin for 1 month, followed by ticagrelor alone, improves outcomes after percutaneous coronary intervention compared with standard antiplatelet regimens.

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
392
Issue :
10151
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs46514668
Full Text :
https://doi.org/10.1016/S0140-6736(18)31858-0