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Metabolic Effects of Betaine: A Randomized Clinical Trial of Betaine Supplementation in Prediabetes

Authors :
Grizales, Ana Maria
Patti, Mary-Elizabeth
Lin, Alexander P
Beckman, Joshua A
Sahni, V Anik
Cloutier, Emilie
Fowler, Kristen M
Dreyfuss, Jonathan M
Pan, Hui
Kozuka, Chisayo
Lee, Adrienne
Basu, Rita
Pober, David M
Gerszten, Robert E
Goldfine, Allison B
Source :
The Journal of Clinical Endocrinology & Metabolism; August 2018, Vol. 103 Issue: 8 p3038-3049, 12p
Publication Year :
2018

Abstract

Betaine improves insulin sensitivity during glucose tolerance testing but has little other metabolic effect. Dimethylglycine dehydrogenase limits betaine metabolism in prediabetes.

Details

Language :
English
ISSN :
0021972X and 19457197
Volume :
103
Issue :
8
Database :
Supplemental Index
Journal :
The Journal of Clinical Endocrinology & Metabolism
Publication Type :
Periodical
Accession number :
ejs46434565
Full Text :
https://doi.org/10.1210/jc.2018-00507