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Muscle O2consumption by NIRS: a theoretical model

Authors :
Binzoni, T.
Colier, W.
Hiltbrand, E.
Hoofd, L.
Cerretelli, P.
Source :
Journal of Applied Physiology; August 1999, Vol. 87 Issue: 2 p683-688, 6p
Publication Year :
1999

Abstract

In the past, the measurement of O2consumption (O˙2) by the muscle could be carried out noninvasively by near-infrared spectroscopy from oxyhemoglobin and/or deoxyhemoglobin measurements only at rest or during steady isometric contractions. In the present study, a mathematical model is developed allowing calculation, together with steady-state levels ofO˙2, of the kinetics of O˙2readjustment in the muscle from the onset of ischemic but aerobic constant-load isotonic exercises. The model, which is based on the known sequence of exoergonic metabolic pathways involved in muscle energetics, allows simultaneous fitting of batched data obtained during exercises performed at different workloads. A Monte Carlo simulation has been carried out to test the quality of the model and to define the most appropriate experimental approach to obtain the best results. The use of a series of experimental protocols obtained at different levels of mechanical power, rather than repetitions of the same load, appears to be the most suitable procedure.

Details

Language :
English
ISSN :
87507587 and 15221601
Volume :
87
Issue :
2
Database :
Supplemental Index
Journal :
Journal of Applied Physiology
Publication Type :
Periodical
Accession number :
ejs46246610
Full Text :
https://doi.org/10.1152/jappl.1999.87.2.683