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Group IIA-Secreted Phospholipase A2in Human Serum Kills Commensal but Not Clinical Enterococcus faeciumIsolates

Authors :
Paganelli, Fernanda L.
Leavis, Helen L.
He, Samantha
van Sorge, Nina M.
Payré, Christine
Lambeau, Gérard
Willems, Rob J. L.
Rooijakkers, Suzan H. M.
Source :
Infection and Immunity; May 2018, Vol. 86 Issue: 8
Publication Year :
2018

Abstract

Human innate immunity employs cellular and humoral mechanisms to facilitate rapid killing of invading bacteria. The direct killing of bacteria by human serum is attributed mainly to the activity of the complement system, which forms pores in Gram-negative bacteria.

Details

Language :
English
ISSN :
00199567 and 10985522
Volume :
86
Issue :
8
Database :
Supplemental Index
Journal :
Infection and Immunity
Publication Type :
Periodical
Accession number :
ejs46070309
Full Text :
https://doi.org/10.1128/IAI.00180-18