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Spirocycle assembly through selective tandem ring closing metathesis reactions

Authors :
Bassindale, Martin J.
Hamley, Peter
Leitner, Andreas
Harrity, Joseph P.A.
Source :
Tetrahedron Letters; January 1999, Vol. 40 Issue: 16 p3247-3250, 4p
Publication Year :
1999

Abstract

A range of functionalised spirocyclic systems have been prepared under mild and neutral conditions by tandem selective ring closing olefin metathesis reactions. Additionally, a marked preference for 5-membered ring closure over 7-membered ring closure was observed which appears to be a result of a kinetically favoured cyclisation process.

Details

Language :
English
ISSN :
00404039
Volume :
40
Issue :
16
Database :
Supplemental Index
Journal :
Tetrahedron Letters
Publication Type :
Periodical
Accession number :
ejs45817188
Full Text :
https://doi.org/10.1016/S0040-4039(99)00375-5