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Receptor Tyrosine Kinase Fusions and BRAF Kinase Fusions are Rare but Actionable Resistance Mechanisms to EGFR Tyrosine Kinase Inhibitors
- Source :
- Journal of Thoracic Oncology; September 2018, Vol. 13 Issue: 9 p1312-1323, 12p
- Publication Year :
- 2018
-
Abstract
- We analyzed a large set of EGFR-mutated (EGFR+) NSCLC to identify and characterize cases with co-occurring kinase fusions as potential resistance mechanisms to EGFR tyrosine kinase inhibitors (TKIs).
Details
- Language :
- English
- ISSN :
- 15560864 and 15561380
- Volume :
- 13
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Journal of Thoracic Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs45761978
- Full Text :
- https://doi.org/10.1016/j.jtho.2018.05.027