Comportamento dei Sulfidrili del Siero Nelle Emolinfopatie Maligne

Sulfhydryls were determined in the serum of 61 patients affected with malignant hemolymphopathies. The mean values were under normal, except for the group of acute leukemias. A particularly marked difference was found between primary acute leukemias and acutizations of chronic myeloid leukemias. In the former, normal mean values and, in most cases, normal initial values were observed, whereas in the latter no cases with normal initial values were found: here, in addition, the lowest mean values were present. In these cases a relation was observed between lowering of sulfhydryl value and degree of the leukemic hyperplasy. In Hodgkin's disease the lowest sulfhydryl values were found to be consistent with a shorter survival.