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Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial
Authors :
Mallewa, Jane Szubert, Alexander J Mugyenyi, Peter Chidziva, Ennie Thomason, Margaret J Chepkorir, Priscilla Abongomera, George Baleeta, Keith Etyang, Anthony Warambwa, Colin Melly, Betty Mudzingwa, Shepherd Kelly, Christine Agutu, Clara Wilkes, Helen Nkomani, Sanele Musiime, Victor Lugemwa, Abbas Pett, Sarah L Bwakura-Dangarembizi, Mutsa Prendergast, Andrew J Gibb, Diana M Walker, A Sarah Berkley, James A Mugyenyi, Peter Kityo, Cissy Musiime, Victor Wavamunno, Priscilla Nambi, Esther Ocitti, Paul Ndigendawani, Milly Kabahenda, Sheila Kemigisa, Mable Acen, Juliet Olebo, David Francis Mpamize, Gordon Amone, Alex Okweny, David Mbonye, Andrew Nambaziira, Florence Rweyora, Angela Kangah, Mary Kabaswahili, Beatrice Abach, James Abongomera, George Omongin, Joseph Aciro, Irene Philliam, Aleti Arach, Beatrice Ocung, Emmanuel Amone, Geoffrey Miles, Peter Adong, Claudia Tumsuiime, Constance Kidega, Patrick Otto, Ben Apio, Florence Baleeta, Keith Mukuye, Andrew Abwola, Mary Ssennono, Fred Baliruno, David Tuhirwe, Stephen Namisi, Ronald Kigongo, Fredrick Kikyonkyo, Dickson Mushahara, Furaha Okweny, David Tusiime, Julian Musiime, Alex Nankya, Agnes Atwongyeire, Dickens Sirikye, Sowal Myalo, Sula Noowe, Nelson Lugemwa, Abbas Kasozi, Mariam Mwebe, Sandra Atwine, Lorna Senkindu, Tapson Natuhurira, Ian Katemba, Chrispus Ninsiima, Emily Acaku, Moses Kyomuhangi, Joy Ankunda, Rogers Tukwasibwe, Deogratious Ayesiga, Lillian Hakim, James Nathoo, Kusum Bwakura-Dangarembizi, Mutsa Reid, Andrew Chidziva, Ennie Mhute, Tawand Tinago, Gloria Bhiri, Joyline Mudzingwa, Shepherd Phiri, Misheck Steamer, John Nhema, Ruth Warambwa, Colin Musoro, Godfrey Mutsai, Shirley Nemasango, Beauty Moyo, Columbus Chitongo, Stuart Rashirai, Kennias Vhembo, Sydney Mlambo, Brian Nkomani, Sanele Ndemera, Buxton Willard, Marko Berejena, Chipo Musodza, Yeukai Matiza, Patience Mudenge, Boniface Guti, Vongai Etyang, Anthony Agutu, Clara Berkley, Jay Maitland, Kathryn Njuguna, Patricia Mwaringa, Shalton Etyang, Timothy Awuondo, Ken Wale, Stephen Shangala, Jimmy Kithunga, Jefwa Mwarumba, Salim Said Maitha, Salma Mutai, Robert Lozi Lewa, Margaret Mwambingu, Gabriel Mwanzu, Alfred Kalama, Connie Latham, Helen Shikuku, Joyce Fondo, Amos Njogu, Anne Khadenge, Connie Mwakisha, Bryan Siika, Abraham Wools-Kaloustian, Kara Nyandiko, Winston Chepkorir-Cheruiyot, Priscilla Sudoi, Allan Wachira, Simon Meli, Betty Karoney, Mercy Nzioka, Agnes Tanui, Michael Mokaya, Martha Ekiru, Wilson Mboya, Chris Mwimali, Dorothy Mengich, Cecilia Choge, Julie Injera, Wilfred Njenga, Kennedy Cherutich, Salinah Anyango Orido, Millicent Omondi Lwande, Gerald Rutto, Peter Mudogo, Alice Kutto, Irene Shali, Amina Jaika, Linda Jerotich, Hellen Pierre, Mowlem Mallewa, Jane Kaunda, Symon Van Oosterhout, Joep O'Hare, Bernadette Heydermann, Robert Gonzalez, Carmen Dzabala, Nettie Kelly, Christine Denis, Brigitte Selemani, George Nyondo- Mipando, Linda Chirwa, Emmie Banda, Peter Mvula, Linley Msuku, Harrison Ziwoya, Milton Manda, Yollam Nicholas, Simon Masesa, Clemens Mwalukomo, Thandi Makhaza, Lumbani Sheha, Irene Bwanali, Joseph Limbuni, Molly Gibb, Diana M Thomason, Margaret J Walker, Ann Sarah Pett, Sarah L Szubert, Alexander J Griffiths, Anna Wilkes, Helen Rajapakse, Chathurika Spyer, Moira J Prendergast, Andrew J Klein, Nigel Rauchenberger, Mary Van Looy, Nadine Little, Emma Fairbrother, Keith Cowan, Frances Seeley, Janet Bernays, Sarah Kawuma, Rachel Mupambireyi, Zivai
Source :
The Lancet HIV; May 2018, Vol. 5 Issue: 5 pe231-e240, 10p
Publication Year :
2018
Abstract
In sub-Saharan Africa, severely immunocompromised HIV-infected individuals have a high risk of mortality during the first few months after starting antiretroviral therapy (ART). We hypothesise that universally providing ready-to-use supplementary food (RUSF) would increase early weight gain, thereby reducing early mortality compared with current guidelines recommending ready-to-use therapeutic food (RUTF) for severely malnourished individuals only.
Details
Language :
English
ISSN :
24054704 and 23523018
Volume :
5
Issue :
5
Database :
Supplemental Index
Journal :
The Lancet HIV
Publication Type :
Periodical
Accession number :
ejs45337940
Full Text :
https://doi.org/10.1016/S2352-3018(18)30038-9