A description of arterial wall mechanics using limiting chain extensibility constitutive models

Abstract:  Certain aspects of the mechanical response of arterial walls can be described using nonlinear elasticity theory. Uniaxial tests on vascular walls reveal nonlinear stress–strain behavior, with higher extensibility in the low stretch range and progressively lower extensibility with increasing stretch. This phenomenon is well known in the framework of rubber-like materials where it is called a strain-hardening or strain-stiffening effect. Constitutive models of incompressible hyperelasticity that take this into account include power-law models and limiting chain extensibility models. Our purpose in this paper is to bring to the attention of the biomechanics community some essential features of one such model of the latter type due to Gent. This model is compared with isotropic versions of biomechanical constitutive models by Takamizawa–Hayashi and Fung; the latter is a limiting version of a power-law material. Two particular problems are considered for which experimental data on arterial wall deformations are available. The first concerns small oscillations superposed on a large static stretch of a vertical string of arterial tissue. It is shown that the exponential model of Fung and the Gent model match well with the experimental data. The second problem is the extension of an internally pressurized circular cylindrical tube. It is shown that an inversion phenomenon observed experimentally for the human iliac artery can be described within a membrane theory by the Gent model whereas this cannot be described using the exponential model. The foregoing considerations are carried out for isotropic elastic materials in the absence of residual stress. Extensions to include anisotropy are also indicated.