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Novel Consecutive β- and γ-Turn Mimetics Composed of α-Aminooxy Tripeptides

Authors :
Baek, B.-h.
Lee, M.-r.
Kim, K.-Y.
Cho, U.-I.
Boo, D. W.
Shin, I.
Source :
Organic Letters; April 2003, Vol. 5 Issue: 7 p971-974, 4p
Publication Year :
2003

Abstract

<UFIGR ID="ol020233qn00002">To develop novel consecutive β- and γ-turn mimetics, we designed and characterized α-aminooxy tripeptides (trimers) consisting of oxanipecotic acid dimer and α-aminooxy acid. According to FT-IR and NMR data, as well as ab initio quantum calculations, the trimers adopted unusual folded structures with consecutive β- and γ-turnlike conformations.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
5
Issue :
7
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs4444761