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Aqueous Extract of Carica Papaya Linn Roots Halts Sodium Arsenite-Induced Renal Inflammation through Inhibiting Adenosine Deaminase, 8-Hydroxy-2′-Deoxyguanosine, C-Reactive Protein and Inducible Nitric Oxide Synthase Activity

Aqueous Extract of Carica Papaya Linn Roots Halts Sodium Arsenite-Induced Renal Inflammation through Inhibiting Adenosine Deaminase, 8-Hydroxy-2′-Deoxyguanosine, C-Reactive Protein and Inducible Nitric Oxide Synthase Activity

Authors :
Ojo, Oluwafemi Adeleke
Ojo, Adebola Busola
Osukoya, Olukemi Adetutu
Ajiboye, Basiru Olaitan
Source :
Serbian Journal of Experimental and Clinical Research; December 2017, Vol. 18 Issue: 4 p323-330, 8p
Publication Year :
2017

Abstract

Objectives:Inflammation plays a crucial role in many of the metabolic abnormalities. The prototypic marker of inflammation is C-reactive protein (CRP), Nitric Oxide (NO), inducible nitric oxide synthase (iNOS) and their inhibition is considered a promising strategy to combat inflammation. Here, we report the anti-inflammatory mechanism of Carica papayaroot aqueous extract in sodium arsenic-induced renal dysfunction.

Details

Language :
English
ISSN :
2335075X and 18208665
Volume :
18
Issue :
4
Database :
Supplemental Index
Journal :
Serbian Journal of Experimental and Clinical Research
Publication Type :
Periodical
Accession number :
ejs44426470
Full Text :
https://doi.org/10.1515/sjecr-2017-0029