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Genetic and Immune Profiles of Solid Predominant Lung Adenocarcinoma Reveal Potential Immunotherapeutic Strategies

Authors :
Dong, Zhong-Yi
Zhang, Chao
Li, Yu-Fa
Su, Jian
Xie, Zhi
Liu, Si-Yang
Yan, Li-Xu
Chen, Zhi-Hong
Yang, Xue-Ning
Lin, Jun-Tao
Tu, Hai-Yan
Yang, Jin-Ji
Zhou, Qing
Sun, Yue-Li
Zhong, Wen-Zhao
Wu, Yi-Long
Source :
Journal of Thoracic Oncology; January 2018, Vol. 13 Issue: 1 p85-96, 12p
Publication Year :
2018

Abstract

Subtype classification of lung adenocarcinoma (LUAD) divides different survivals and therapeutic vulnerabilities; however, little is known about the disease’s underlying molecular mechanism. This study sought to determine the genetic and immune profiles of histologic subtypes and identify the evidence for adjuvant immunotherapy.

Details

Language :
English
ISSN :
15560864 and 15561380
Volume :
13
Issue :
1
Database :
Supplemental Index
Journal :
Journal of Thoracic Oncology
Publication Type :
Periodical
Accession number :
ejs43847366
Full Text :
https://doi.org/10.1016/j.jtho.2017.10.020