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Non-invasive fetal RHDgenotyping for RhD negative women stratified into RHDgene deletion or variant groups: comparative accuracy using two blood collection tube types

Authors :
Hyland, Catherine A.
Millard, Glenda M.
O'Brien, Helen
Schoeman, Elizna M.
Lopez, Genghis H.
McGowan, Eunike C.
Tremellen, Anne
Puddephatt, Rachel
Gaerty, Kirsten
Flower, Robert L.
Hyett, Jonathan A.
Gardener, Glenn J.
Source :
Pathology; December 2017, Vol. 49 Issue: 7 p757-764, 8p
Publication Year :
2017

Abstract

Non-invasive fetal RHDgenotyping in Australia to reduce anti-D usage will need to accommodate both prolonged sample transport times and a diverse population demographic harbouring a range of RHDblood group gene variants. We compared RHDgenotyping accuracy using two blood sample collection tube types for RhD negative women stratified into deleted RHDgene haplotype and RHDgene variant cohorts.

Details

Language :
English
ISSN :
00313025 and 14653931
Volume :
49
Issue :
7
Database :
Supplemental Index
Journal :
Pathology
Publication Type :
Periodical
Accession number :
ejs43354668
Full Text :
https://doi.org/10.1016/j.pathol.2017.08.010