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Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury

Authors :
Moledina, Dennis G.
Hall, Isaac E.
Thiessen-Philbrook, Heather
Reese, Peter P.
Weng, Francis L.
Schröppel, Bernd
Doshi, Mona D.
Wilson, F. Perry
Coca, Steven G.
Parikh, Chirag R.
Source :
American Journal of Kidney Diseases; December 2017, Vol. 70 Issue: 6 p807-816, 10p
Publication Year :
2017

Abstract

The diagnosis of acute kidney injury (AKI), which is currently defined as an increase in serum creatinine (Scr) concentration, provides little information on the condition’s actual cause. To improve phenotyping of AKI, many urinary biomarkers of tubular injury are being investigated. Because AKI cases are not frequently biopsied, the diagnostic accuracy of concentrations of Scr and urinary biomarkers for histologic acute tubular injury is unknown.

Details

Language :
English
ISSN :
02726386 and 15236838
Volume :
70
Issue :
6
Database :
Supplemental Index
Journal :
American Journal of Kidney Diseases
Publication Type :
Periodical
Accession number :
ejs42895545
Full Text :
https://doi.org/10.1053/j.ajkd.2017.06.031