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C4 Nephritic Factors in C3 Glomerulopathy: A Case Series

Authors :
Zhang, Yuzhou
Meyer, Nicole C.
Fervenza, Fernando C.
Lau, Winnie
Keenan, Adam
Cara-Fuentes, Gabriel
Shao, Dingwu
Akber, Aalia
Fremeaux-Bacchi, Veronique
Sethi, Sanjeev
Nester, Carla M.
Smith, Richard J.H.
Source :
American Journal of Kidney Diseases; December 2017, Vol. 70 Issue: 6 p834-843, 10p
Publication Year :
2017

Abstract

C3 glomerulopathy (C3G) defines a group of rare complement-mediated kidney diseases with a shared underlying pathophysiology: dysregulation of complement in the fluid phase and glomerular microenvironment. Dysregulation can be driven by autoantibodies to C3 and C5 convertases.

Details

Language :
English
ISSN :
02726386 and 15236838
Volume :
70
Issue :
6
Database :
Supplemental Index
Journal :
American Journal of Kidney Diseases
Publication Type :
Periodical
Accession number :
ejs42876447
Full Text :
https://doi.org/10.1053/j.ajkd.2017.07.004