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Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial
- Source :
- The Lancet Diabetes & Endocrinology; August 2017, Vol. 5 Issue: 8 p597-609, 13p
- Publication Year :
- 2017
-
Abstract
- Metformin might reduce insulin requirement and improve glycaemia in patients with type 1 diabetes, but whether it has cardiovascular benefits is unknown. We aimed to investigate whether metformin treatment (added to titrated insulin therapy) reduced atherosclerosis, as measured by progression of common carotid artery intima-media thickness (cIMT), in adults with type 1 diabetes at increased risk for cardiovascular disease.
Details
- Language :
- English
- ISSN :
- 22138587 and 22138595
- Volume :
- 5
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- The Lancet Diabetes & Endocrinology
- Publication Type :
- Periodical
- Accession number :
- ejs42818767
- Full Text :
- https://doi.org/10.1016/S2213-8587(17)30194-8