Serous cystadenocarcinoma of the pancreas and serous cystadenoma associated with ductal pancreatic adenocarcinoma

Serous cystadenoma of the pancreas is commonly considered to be a benign neoplasm and therefore a more conservative surgical attitude is suggested, leaving resection for symptomatic patients or those who develop complications. Recently some malignant forms of serous cystadenoma leading to liver metastasis, perineural invasion and vascular invasion have been reported, thus challenging the benign status of serous cystadenomas.