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Acceleration of Phagocytosis in Human Neutrophils Incubated with Gabexate Mesilate
- Source :
- Journal of International Medical Research; September 1994, Vol. 22 Issue: 5 p292-295, 4p
- Publication Year :
- 1994
-
Abstract
- It has recently been shown that gabexate mesilate inhibited human neutrophil functions including chemotaxis and reactive oxygen species production. In the present study, the effects of gabexate mesilate on phagocytosis by human neutrophils in vitrowere investigated. Gabexate mesilate significantly enhanced neutrophil phagocytosis in a dose-dependent manner. This characteristic of gabexate mesilate may facilitate protection against infecting micro-organisms, although the inhibition of reactive oxygen species production by neutrophils may be a disadvantage for host-defense against infection.
Details
- Language :
- English
- ISSN :
- 03000605 and 14732300
- Volume :
- 22
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of International Medical Research
- Publication Type :
- Periodical
- Accession number :
- ejs42308905
- Full Text :
- https://doi.org/10.1177/030006059402200507