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Cimetidine—A Non-Thiourea H2-Receptor Antagonist

Authors :
Brimblecombe, R W
Duncan, W A M
Durant, G J
Emmett, J C
Ganellin, C R
Parsons, M E
Source :
Journal of International Medical Research; March 1975, Vol. 3 Issue: 2 p86-92, 7p
Publication Year :
1975

Abstract

Cimetidine is a non-thiourea analogue of metiamide. It is a specific competitive histamine H2-receptor antagonist and is an effective inhibitor of gastric secretion in animals and man with similar pharmacological properties to metiamide. No renal damage or haematological changes were observed in 90-day studies in rats or dogs.

Details

Language :
English
ISSN :
03000605 and 14732300
Volume :
3
Issue :
2
Database :
Supplemental Index
Journal :
Journal of International Medical Research
Publication Type :
Periodical
Accession number :
ejs42295003
Full Text :
https://doi.org/10.1177/030006057500300205