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Oxidative Damage to Nucleic Acids in Severe Emphysema

Authors :
Deslee, Gaetan
Woods, Jason C.
Moore, Carla
Conradi, Susan H.
Gierada, David S.
Atkinson, Jeffrey J.
Battaile, John T.
Liu, Lucy
Patterson, G. Alexander
Adair-Kirk, Tracy L.
Holtzman, Michael J.
Pierce, Richard A.
Source :
Chest; April 2009, Vol. 135 Issue: 4 p965-974, 10p
Publication Year :
2009

Abstract

Oxidative stress is a key element in the pathogenesis of emphysema, but oxidation of nucleic acids has been largely overlooked. The aim of this study was to investigate oxidative damage to nucleic acids in severe emphysematous lungs.

Details

Language :
English
ISSN :
00123692 and 19313543
Volume :
135
Issue :
4
Database :
Supplemental Index
Journal :
Chest
Publication Type :
Periodical
Accession number :
ejs42080016
Full Text :
https://doi.org/10.1378/chest.08-2257