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Infrequent Involvement of P53 Mutations and Loss of Heterozygosity of 17p in the Tumorigenesis of Renal Cell Carcinoma

Infrequent Involvement of P53 Mutations and Loss of Heterozygosity of 17p in the Tumorigenesis of Renal Cell Carcinoma

Authors :
Uchida, Toyoaki
Wada, Chieki
Shitara, Toshiya
Egawa, Shin
Mashimo, Setsuo
Koshiba, Ken
Source :
The Journal of Urology; October 1993, Vol. 150 Issue: 4 p1298-1301, 4p
Publication Year :
1993

Abstract

Restriction fragment length polymorphism (RFLP) analysis and the polymerase chain reaction of the single-strand conformation polymorphism (PCR-SSCP) method were conducted to assess the loss of heterozygosity of chromosome 17p and mutations of the p53 gene in 30 surgical specimens of human renal cell carcinoma.

Details

Language :
English
ISSN :
00225347 and 15273792
Volume :
150
Issue :
4
Database :
Supplemental Index
Journal :
The Journal of Urology
Publication Type :
Periodical
Accession number :
ejs42034449
Full Text :
https://doi.org/10.1016/S0022-5347(17)35764-6