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Prominent expression of <TOGGLE>lysyl oxidase</TOGGLE> during mouse embryonic cardiovascular development

Authors :
Tsuda, Takeshi
Pan, Te-Cheng
Evangelisti, Lucia
Source :
The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology; February 2003, Vol. 270 Issue: 2 p93-96, 4p
Publication Year :
2003

Abstract

By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (E11) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium. Anat Rec Part A 270A:93–96, 2003. &#169; 2003 Wiley-Liss, Inc.

Details

Language :
English
ISSN :
15524884 and 15524892
Volume :
270
Issue :
2
Database :
Supplemental Index
Journal :
The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology
Publication Type :
Periodical
Accession number :
ejs4202453
Full Text :
https://doi.org/10.1002/ar.a.10002