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Durability of viral suppression with first-line antiretroviral therapy in patients with HIV in the UK: an observational cohort study

Authors :
O'Connor, Jemma
Smith, Colette
Lampe, Fiona C
Johnson, Margaret A
Chadwick, David R
Nelson, Mark
Dunn, David
Winston, Alan
Post, Frank A
Sabin, Caroline
Phillips, Andrew N
Ainsworth, Jonathan
Allan, Sris
Anderson, Jane
Babiker, Abdel
Chadwick, David
Delpech, Valerie
Dunn, David
Fisher, Martin
Gazzard, Brian
Gilson, Richard
Gompels, Mark
Hay, Phillip
Hill, Teresa
Johnson, Margaret
Jose, Sophie
Kegg, Stephen
Leen, Clifford
Martin, Fabiola
Nelson, Mark
Orkin, Chloe
Palfreeman, Adrian
Phillips, Andrew
Pillay, Deenan
Post, Frank
Pritchard, Jillian
Sabin, Caroline
Sachikonye, Memory
Schwenk, Achim
Tariq, Anjum
Trevelion, Roy
Walsh, John
Glabay, A
Perry, N
Tilbury, S
Youssef, E
Churchill, D
Gazzard, B
Nelson, M
Everett, R
Asboe, D
Mandalia, S
Post, F
Korat, H
Taylor, C
Gleisner, Z
Ibrahim, F
Campbell, L
Gilson, R
Brima, N
Williams, I
Johnson, M
Youle, M
Lampe, F
Smith, C
Tsintas, R
Chaloner, C
Hutchinson, S
Sabin, C
Phillips, A
Hill, T
Jose, S
Thornton, A
Huntington, S
Walsh, J
Mackie, N
Winston, A
Weber, J
Ramzan, F
Carder, M
Orkin, C
Lynch, J
Hand, J
de Souza, C
Anderson, J
Munshi, S
Ainsworth, J
Schwenk, A
Miller, S
Wood, C
Leen, C
Wilson, A
Morris, S
Gompels, M
Allan, S
Palfreeman, A
Memon, K
Lewszuk, A
Chadwick, D
Cope, E
Gibson, J
Kegg, S
Main, P
Mitchell, S
Hunter, M
Dhillon, M
Martin, F
Russell-Sharpe, S
Allan, S
Harte, A
Clay, S
Tariq, A
Spencer, H
Jones, R
Pritchard, J
Cumming, S
Atkinson, C
Delpech, V
Source :
The Lancet HIV; July 2017, Vol. 4 Issue: 7 pe295-e302, 8p
Publication Year :
2017

Abstract

The length of time that people with HIV on antiretroviral therapy (ART) with viral load suppression will be able to continue before developing viral rebound is unknown. We aimed to investigate the rate of first viral rebound in people that have achieved initial suppression with ART, to determine factors associated with viral rebound, and to use these estimates to predict long-term durability of viral suppression.

Details

Language :
English
ISSN :
24054704 and 23523018
Volume :
4
Issue :
7
Database :
Supplemental Index
Journal :
The Lancet HIV
Publication Type :
Periodical
Accession number :
ejs41882191
Full Text :
https://doi.org/10.1016/S2352-3018(17)30053-X