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Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials

Authors :
Costa, Francesco
van Klaveren, David
James, Stefan
Heg, Dik
Räber, Lorenz
Feres, Fausto
Pilgrim, Thomas
Hong, Myeong-Ki
Kim, Hyo-Soo
Colombo, Antonio
Steg, Philippe Gabriel
Zanchin, Thomas
Palmerini, Tullio
Wallentin, Lars
Bhatt, Deepak L
Stone, Gregg W
Windecker, Stephan
Steyerberg, Ewout W
Valgimigli, Marco
Source :
The Lancet; March 2017, Vol. 389 Issue: 10073 p1025-1034, 10p
Publication Year :
2017

Abstract

Dual antiplatelet therapy (DAPT) with aspirin plus a P2Y12inhibitor prevents ischaemic events after coronary stenting, but increases bleeding. Guidelines support weighting bleeding risk before the selection of treatment duration, but no standardised tool exists for this purpose.

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
389
Issue :
10073
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs41499128
Full Text :
https://doi.org/10.1016/S0140-6736(17)30397-5