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Clinical and Molecular Epidemiology of Acinetobacter BaumanniiBloodstream Infections in an Endemic Setting
- Source :
- Future Microbiology; March 2017, Vol. 12 Issue: 4 p271-283, 13p
- Publication Year :
- 2017
-
Abstract
- Aim:The transmission dynamics of Acinetobacter baumanniiin endemic settings, and the relation between microbial properties and patients’ clinical outcomes, are yet obscure and hampered by insufficient metadata. Methods & Results:Of 20 consecutive patients with A. baumanniibloodstream infection that were thoroughly analyzed at a single center, at least one transmission opportunity was evident for 85% of patients. This implies that patient-to-patient transmission is the major mode of A. baumanniiacquisitions in health facilities. Moreover, all patients who died immediately (<24 h of admission) were infected with a single clone (ST457; relative risk = 1.6; p = 0.05). Conclusion:This preliminary analysis should prompt further investigation by mapping genomic virulence determinants among A. baumanniiST457 lineage compared with other strains.
Details
- Language :
- English
- ISSN :
- 17460913 and 17460921
- Volume :
- 12
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Future Microbiology
- Publication Type :
- Periodical
- Accession number :
- ejs41389490
- Full Text :
- https://doi.org/10.2217/fmb-2016-0158