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APOL1genotype, blood pressure, and survival in African Americans with nondiabetic nephropathy
- Source :
- Kidney International; February 2017, Vol. 91 Issue: 2 p276-278, 3p
- Publication Year :
- 2017
-
Abstract
- Several landmark trials have assessed the effects of aggressive hypertension control on the progression of nondiabetic chronic kidney disease. Results generally have been disappointing. With the realization that lowering blood pressure, including with renin-angiotensin system blockade, failed to reliably prevent end-stage kidney disease, studies now are analyzing longer-term effects of hypertension control on survival in chronic kidney disease. This commentary reviews the current findings and extends the discussion to apolipoprotein L1 gene by blood pressure (or gene by environment) interactions.
Details
- Language :
- English
- ISSN :
- 00852538 and 15231755
- Volume :
- 91
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Kidney International
- Publication Type :
- Periodical
- Accession number :
- ejs40500408
- Full Text :
- https://doi.org/10.1016/j.kint.2016.10.027