Symptomatology Subscales for the Measurement of Acute Mountain Sickness

Additional information regarding the development of symptomatology subscales for the measurement of Acute Mountain Sickness (AMS) is presented. High item intercorrelations and strong factor loadings of items comprising symptom clusters (i.e., Arousal Level, Somatic Discomfort, Tired, and Mood) support the previously reported breakdown of the General High Altitude Questionnaire (GHAQ) into subscales. Rapid transition from low to high altitude resulted in an increase of these symptomatology subscale scores. Several subscale differences were also noted between Phenformin and Placebo Ss at low altitude. Such subscale measures could provide improved estimates of symptomatology, useful in assessing the effectiveness of various treatments intended to ameliorate AMS.