Back to Search Start Over

Resolving TYK2locus genotype-to-phenotype differences in autoimmunity

Authors :
Dendrou, Calliope A.
Cortes, Adrian
Shipman, Lydia
Evans, Hayley G.
Attfield, Kathrine E.
Jostins, Luke
Barber, Thomas
Kaur, Gurman
Kuttikkatte, Subita Balaram
Leach, Oliver A.
Desel, Christiane
Faergeman, Soren L.
Cheeseman, Jane
Neville, Matt J.
Sawcer, Stephen
Compston, Alastair
Johnson, Adam R.
Everett, Christine
Bell, John I.
Karpe, Fredrik
Ultsch, Mark
Eigenbrot, Charles
McVean, Gil
Fugger, Lars
Source :
Science Translational Medicine; November 2016, Vol. 8 Issue: 363 p363ra149-363ra149, 1p
Publication Year :
2016

Abstract

Resolving TYK2locus genotype-to-phenotype differences reveals an immune signaling optimum that may be exploited therapeutically for treating autoimmune diseases.

Details

Language :
English
ISSN :
19466234 and 19466242
Volume :
8
Issue :
363
Database :
Supplemental Index
Journal :
Science Translational Medicine
Publication Type :
Periodical
Accession number :
ejs40370030
Full Text :
https://doi.org/10.1126/scitranslmed.aag1974