NAD+repletion improves muscle function in muscular dystrophy and counters global PARylation

Authors :: Ryu, Dongryeol
Zhang, Hongbo
Ropelle, Eduardo R.
Sorrentino, Vincenzo
Mázala, Davi A. G.
Mouchiroud, Laurent
Marshall, Philip L.
Campbell, Matthew D.
Ali, Amir Safi
Knowels, Gary M.
Bellemin, Stéphanie
Iyer, Shama R.
Wang, Xu
Gariani, Karim
Sauve, Anthony A.
Cantó, Carles
Conley, Kevin E.
Walter, Ludivine
Lovering, Richard M.
Chin, Eva R.
Jasmin, Bernard J.
Marcinek, David J.
Menzies, Keir J.
Auwerx, Johan
Source :: Science Translational Medicine; October 2016, Vol. 8 Issue: 361 p361ra139-361ra139, 1p
Publication Year :: 2016
Abstract: NAD+treatment can reverse the functional decline in degenerating muscles.

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