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Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

Authors :
Dejnirattisai, Wanwisa
Supasa, Piyada
Wongwiwat, Wiyada
Rouvinski, Alexander
Barba-Spaeth, Giovanna
Duangchinda, Thaneeya
Sakuntabhai, Anavaj
Cao-Lormeau, Van-Mai
Malasit, Prida
Rey, Felix A
Mongkolsapaya, Juthathip
Screaton, Gavin R
Source :
Nature Immunology; September 2016, Vol. 17 Issue: 9 p1102-1108, 7p
Publication Year :
2016

Abstract

Infection with Zika virus has occurred in areas previously exposed to dengue virus, a closely related flavivirus. Screaton and colleagues find that monoclonal antibodies to dengue virus cross-react with Zika virus and enhance infection.

Details

Language :
English
ISSN :
15292908 and 15292916
Volume :
17
Issue :
9
Database :
Supplemental Index
Journal :
Nature Immunology
Publication Type :
Periodical
Accession number :
ejs39853245
Full Text :
https://doi.org/10.1038/ni.3515