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Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites
- Source :
- Molecular Biology of the Cell; August 2016, Vol. 27 Issue: 15 p2435-2449, 15p
- Publication Year :
- 2016
-
Abstract
- Loss of VPS13produces multiple phenotypes. This study implicates VPS13in the function of membrane contact sites and suggests that different phenotypes of the mutant result from defects in different contact sites. In yeast, mutations found in the VPS13Agene of ChAc patients have specific defects in the mitochondrial aspect of VPS13function.
Details
- Language :
- English
- ISSN :
- 10591524 and 19394586
- Volume :
- 27
- Issue :
- 15
- Database :
- Supplemental Index
- Journal :
- Molecular Biology of the Cell
- Publication Type :
- Periodical
- Accession number :
- ejs39731379
- Full Text :
- https://doi.org/10.1091/mbc.E16-02-0112