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Thermal compression and molding of atherosclerotic vascular tissue with use of radiofrequency energy: Implications for radiofrequency balloon angioplasty
- Source :
- Journal of the American College of Cardiology; April 1989, Vol. 13 Issue: 5 p1167-1175, 9p
- Publication Year :
- 1989
-
Abstract
- The combined delivery of pressure and thermal energy may effectively remodel intraluminal atherosclerotic plaque and fuse intimal tears. To test these hypotheses with use of a non-laser thermal energy source, radiofrequency energy was delivered to postmortem human atherosclerotic vessels from a metal “hot-tip” catheter, block-mounted bipolar electrodes and from a prototype radiofrequency balloon catheter. Sixty-two radiofrequency doses delivered from a metal electrode tip produced dose-dependent ablation of atherosclerotic plaque, ranging from clean and shallow craters with histologic evidence of thermal compression at doses <40 J to tissue charring and vaporization at higher (>80 J) doses. Lesion dimensions ranged between 3.14 and 3.79 mm in diameter and 0.20 and 0.47 mm in depth. Tissue perforation was not observed.
Details
- Language :
- English
- ISSN :
- 07351097 and 15583597
- Volume :
- 13
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of the American College of Cardiology
- Publication Type :
- Periodical
- Accession number :
- ejs39664396
- Full Text :
- https://doi.org/10.1016/0735-1097(89)90280-5