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ChemInform Abstract: Golfomycin A, a Novel Designed Molecule with DNA‐Cleaving Properties and Antitumor Activity.

Authors :
NICOLAOU, K. C.
SKOKOTAS, G.
FURAYA, S.
SUEMUNE, H.
NICOLAOU, D. C.
Source :
ChemInform; December 1990, Vol. 21 Issue: 49 pno-no
Publication Year :
1990

Abstract

Starting with the Grignard reagent (I) the synthesis of the title compound golfomycin A (VI) is described, the design of which is the result of mechanistic considerations concerning DNA‐cleaving and antitumor properties.

Details

Language :
English
ISSN :
09317597 and 15222667
Volume :
21
Issue :
49
Database :
Supplemental Index
Journal :
ChemInform
Publication Type :
Periodical
Accession number :
ejs39210242
Full Text :
https://doi.org/10.1002/chin.199049149