ChemInform Abstract: Pyridonecarboxylic Acids as Antibacterial Agents. Part 2. Synthesis and Structure‐Activity Relationship of 1‐(4‐Hydroxyphenyl)‐6‐substituted‐4‐ pyridone‐3‐carboxylic Acids. Pyridonecarboxylic Acids as Antibacterial Agents. Part 3. Synthesis and Structure‐Activity Relationship of 1‐(4‐ Fluorophenyl)‐ and 1‐(2,4‐Difluorophenyl)‐6‐substituted‐4‐pyridone‐3‐ carboxylic Acids.

Authors :: NARITA, H.
KONISHI, Y.
NITTA, J.
KOBAYASHI, Y.
WATANABE, Y.
MINAMI, S.
SAIKAWA, I.
MIYAZIMA, M.
YOTSUJI, A.
Source :: ChemInform; April 1987, Vol. 18 Issue: 16 pno-no
Publication Year :: 1987
Abstract: The 4‐pyridone‐3‐carboxylic acids (VII) are prepared by Wittig reaction, coupling of the olefins (III) with the acetal (IV) and the anilines (V), followed by cyclization.