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The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
- Source :
- Nature; April 2016, Vol. 532 Issue: 7598 p245-249, 5p
- Publication Year :
- 2016
-
Abstract
- A study of pancreatic ductal adenocarcinoma shows that cancer cell proliferation is associated with increased expression of proteins that control programmed necrotic cell death and suppress the adaptive immune system.
Details
- Language :
- English
- ISSN :
- 00280836 and 14764687
- Volume :
- 532
- Issue :
- 7598
- Database :
- Supplemental Index
- Journal :
- Nature
- Publication Type :
- Periodical
- Accession number :
- ejs38556018
- Full Text :
- https://doi.org/10.1038/nature17403