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Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ

Authors :
Surve, Chinmay R.
To, Jesi Y.
Malik, Sundeep
Kim, Minsoo
Smrcka, Alan V.
Source :
Science Signaling; February 2016, Vol. 9 Issue: 416 pra22-ra22, 1p
Publication Year :
2016

Abstract

Opposing effects of Giprotein α and βγ subunits on the abundance of the second messenger cAMP enable neutrophil migration.

Details

Language :
English
ISSN :
19450877 and 19379145
Volume :
9
Issue :
416
Database :
Supplemental Index
Journal :
Science Signaling
Publication Type :
Periodical
Accession number :
ejs38149384
Full Text :
https://doi.org/10.1126/scisignal.aad8163