Coating Pharmaceuticals by Coacervation

The objectives of this study were to investigate the phenomenon of coacervation as a new means of coating pharmaceuticals and to develop procedures of operation for coating some commonly used drugs. Factors affecting coacervate drop size, some methods of regulating coating thickness, and techniques of controlling the volume of the coacervate produced were determined. Using sodium sulfate solutions and gelatin solutions as the coacervating liquids, five solids and two liquids were coated and processed to produce dry powders.