Back to Search Start Over

Antimanic Treatment With Tamoxifen Affects Brain Chemistry: A Double-Blind, Placebo-Controlled Proton Magnetic Resonance Spectroscopy Study

Authors :
Yildiz, Ayşegül
Aydin, Burç
Gökmen, Necati
Yurt, Ayşegül
Cohen, Bruce
Keskinoglu, Pembe
Öngür, Dost
Renshaw, Perry
Source :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging; March 2016, Vol. 1 Issue: 2 p125-131, 7p
Publication Year :
2016

Abstract

The antimanic efficacy of a protein kinase C inhibitor, tamoxifen, has been tested in several clinical trials, all reporting positive results. However, mechanisms underlying the observed clinical effects require further confirmation through studies of biological markers.

Details

Language :
English
ISSN :
24519022
Volume :
1
Issue :
2
Database :
Supplemental Index
Journal :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Publication Type :
Periodical
Accession number :
ejs37542735
Full Text :
https://doi.org/10.1016/j.bpsc.2015.12.002