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Galactomannan enzyme immunoassay and quantitative Real Time PCR as tools to evaluate the exposure and response in a rat model of aspergillosis after posaconazole prophylaxis

Authors :
Cendejas-Bueno, Emilio
Forastiero, Agustina
Ruiz, Isabel
Mellado, Emilia
Buitrago, María José
Gavaldà, Joan
Gomez-Lopez, Alicia
Source :
Enfermedades Infecciosas y Microbiología Clínica (ScienceDirect); November 2016, Vol. 34 Issue: 9 p571-576, 6p
Publication Year :
2016

Abstract

A steroid-immunosuppressed rat model of invasive pulmonary aspergillosis was use to examine the usefulness of galactomannan enzyme immunoassay (GM) and quantitative real time PCR (RT-PCR) in evaluating the association between response and exposure after a high dose of prophylactic posaconazole.

Details

Language :
English
ISSN :
0213005X and 15781852
Volume :
34
Issue :
9
Database :
Supplemental Index
Journal :
Enfermedades Infecciosas y Microbiología Clínica (ScienceDirect)
Publication Type :
Periodical
Accession number :
ejs37492801
Full Text :
https://doi.org/10.1016/j.eimc.2015.11.008