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Design, synthesis and biological evaluation of novel dicarbonylalkyl piperazine derivatives as neuroprotective agents
- Source :
- Chinese Chemical Letters; March 2016, Vol. 27 Issue: 3 p387-390, 4p
- Publication Year :
- 2016
-
Abstract
- Methyl or methoxy introduction compounds like 7oor 7fprovided higher anti-ischemic stroke activity than lead compound 1, while methylene introduction compounds like 7b, 7eand 7rshowed loss of activity.
Details
- Language :
- English
- ISSN :
- 10018417
- Volume :
- 27
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Chinese Chemical Letters
- Publication Type :
- Periodical
- Accession number :
- ejs37255797
- Full Text :
- https://doi.org/10.1016/j.cclet.2015.11.002