Back to Search
Start Over
Synthetic Small Molecules Targeting G-Quadruplexes and their Application
- Source :
- Advanced Materials Research; February 2015, Vol. 1088 Issue: 1 p507-513, 7p
- Publication Year :
- 2015
-
Abstract
- G-quadruplex is expected to be a promising target for drug design. The manually synthesized small-molecule compounds are able to induce the formation of and stabilize G-quadruplexes. In this paper, we summarize the current understanding of the structure of G-quadruplexes, the binding mode of G-quadruplexes and small-molecule ligands, and important synthesized small molecules targeting G-quadruplexes as potential drugs.
Details
- Language :
- English
- ISSN :
- 10226680
- Volume :
- 1088
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Advanced Materials Research
- Publication Type :
- Periodical
- Accession number :
- ejs36646966
- Full Text :
- https://doi.org/10.4028/www.scientific.net/AMR.1088.507