Comparison of the Vidas C. difficileGDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluDfor Detection of Clostridium difficilein Fecal Samples

ABSTRACTPrevention and management of Clostridium difficileinfection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficileglutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis.