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Sevoflurane preconditions stunned myocardium in septic but not healthy isolated rat hearts.

Authors :
Serita, R
Morisaki, H
Ai, K
Morita, Y
Innami, Y
Satoh, T
Kosugi, S
Kotake, Y
Takeda, J
Source :
BJA: British Journal of Anaesthesia; December 2002, Vol. 89 Issue: 6 p896-903, 8p
Publication Year :
2002

Abstract

Recent evidence indicates that sevoflurane treatment before prolonged ischaemia reduces infarct size in normal hearts, mimicking ischaemic preconditioning. We examined whether exposure to sevoflurane before brief ischaemia, inducing a 'stunned myocardium', provided such protective effects in an isolated working heart from normal or septic rats.

Details

Language :
English
ISSN :
00070912 and 14716771
Volume :
89
Issue :
6
Database :
Supplemental Index
Journal :
BJA: British Journal of Anaesthesia
Publication Type :
Periodical
Accession number :
ejs35862025
Full Text :
https://doi.org/10.1093/bja/aef282