DISTURBED MITOTIC PROCESSES OF STROMA CELLS IN A PATIENT WITH TUBEROUS SCLEROSIS

Skin fragments of a giant molluscum pendulum and so‐called adenomata sebacea (AS) in the face of a 21‐year‐old female with Pringle's disease were explanted and the cell divisions of outgrown and subcultured non‐epithelial cells (NECs) were observed at suitable intervals with a phase contrast microscope. In both tissues, a number of NECs, especially large and medium sized ones, showed distinct chromosome dysarrangements, including segmental arrangement, eccentric arrangement, and arrangement failure, when chromosomes were arranged in the central area of individual cells in metaphase, causing extreme lagging in the subsequent cell division.