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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors

Authors :
Egbertson, M. S.
Bednar, B.
Askew, B. C.
Bednar, R. A.
Brashear, K.
Breslin, M. J.
Duggan, M. E.
Fisher, T. E.
Halczenko, W.
Hutchinson, J. H.
Source :
Bioorganic & Medicinal Chemistry Letters; 2000, Vol. 10 Issue: 17 p1943-1948, 6p
Publication Year :
2000

Details

Language :
English
ISSN :
0960894X and 14643405
Volume :
10
Issue :
17
Database :
Supplemental Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Periodical
Accession number :
ejs3508889
Full Text :
https://doi.org/10.1016/S0960-894X(00)00385-1