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Evaluation of the Luciferase Assay-Based In VitroElicitation Test for Serum IgE
- Source :
- Allergology International; January 2012, Vol. 61 Issue: 3 p431-437, 7p
- Publication Year :
- 2012
-
Abstract
- An in vitroelicitation test employing human high-affinity IgE receptor-expressing rat mast cell lines appears to be a useful method for measuring mast cell activation using a patient's IgE and an allergen; however, such cell lines are sensitive to human complements in the serum. We have recently developed a new luciferase-reporting mast cell line (RS-ATL8) to detect IgE crosslinking-induced luciferase expression (EXiLE) with relatively low quantities of serum IgE.
Details
- Language :
- English
- ISSN :
- 13238930 and 14401592
- Volume :
- 61
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Allergology International
- Publication Type :
- Periodical
- Accession number :
- ejs35086869
- Full Text :
- https://doi.org/10.2332/allergolint.11-OA-0407