Back to Search
Start Over
Neutralizing BAFF/APRIL With Atacicept Prevents Early DSA Formation and AMR Development in T Cell Depletion Induced Nonhuman Primate AMR Model
- Source :
- American Journal of Transplantation; March 2015, Vol. 15 Issue: 3 p815-822, 8p
- Publication Year :
- 2015
-
Abstract
- The authors demonstrate in a depletion‐based nonhuman primate renal transplantation model that neutralizing BAFF/APRIL with atacicept decreases donor‐specific antibodies and B cell numbers during active treatment, thus diminishing the overall humoral response after transplantation.
Details
- Language :
- English
- ISSN :
- 16006135 and 16006143
- Volume :
- 15
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- American Journal of Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs34967831
- Full Text :
- https://doi.org/10.1111/ajt.13045