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A high-throughput in vivomicronucleus assay for genome instability screening in mice
- Source :
- Nature Protocols; January 2015, Vol. 10 Issue: 1 p205-215, 11p
- Publication Year :
- 2015
-
Abstract
- This protocol describes a sensitive, robust, high-throughput method for quantifying the formation of micronuclei in mouse erythrocytes. It detects low levels of genome instability and can be used to identify novel genome maintenance genes and models.
Details
- Language :
- English
- ISSN :
- 17542189 and 17502799
- Volume :
- 10
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Nature Protocols
- Publication Type :
- Periodical
- Accession number :
- ejs34580471
- Full Text :
- https://doi.org/10.1038/nprot.2015.010