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Influence of sex and age on febrile responses to peripheral and central administration of pyrogens in the rabbit
- Source :
- Journal of Physiology; October 1979, Vol. 295 Issue: 1 p263-272, 10p
- Publication Year :
- 1979
-
Abstract
- 1. Intravenous injections of leucocytic pyrogen in doses of 15, 30 and 60 μl./kg caused febrile reactions in male rabbits that were related to age of the animal: rabbits under 2 yr of age developed fevers that were related to dose of pyrogen, while rabbits 2‐3 yr old showed large febrile responses which were not dose‐related.
Details
- Language :
- English
- ISSN :
- 00223751 and 14697793
- Volume :
- 295
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Journal of Physiology
- Publication Type :
- Periodical
- Accession number :
- ejs34447583
- Full Text :
- https://doi.org/10.1113/jphysiol.1979.sp012967