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Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study

Authors :
Lawitz, Eric
Sulkowski, Mark S
Ghalib, Reem
Rodriguez-Torres, Maribel
Younossi, Zobair M
Corregidor, Ana
DeJesus, Edwin
Pearlman, Brian
Rabinovitz, Mordechai
Gitlin, Norman
Lim, Joseph K
Pockros, Paul J
Scott, John D
Fevery, Bart
Lambrecht, Tom
Ouwerkerk-Mahadevan, Sivi
Callewaert, Katleen
Symonds, William T
Picchio, Gaston
Lindsay, Karen L
Beumont, Maria
Jacobson, Ira M
Source :
The Lancet; November 2014, Vol. 384 Issue: 9956 p1756-1765, 10p
Publication Year :
2014

Abstract

Interferon-free regimens are needed to treat hepatitis C virus (HCV) infections. We investigated the efficacy of combined simeprevir and sofosbuvir.

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
384
Issue :
9956
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs33445746
Full Text :
https://doi.org/10.1016/S0140-6736(14)61036-9